Ngwaahịa
2,4-Diamino-6-hydroxypyrimidine 2,6-Diamino-4-Hydroxyprimidine
Okwu: 4 (1H) -Pyrimidinone,2,6-diamino- (8CI,9CI);2,4-Diamino-6-hydroxypyrimidine;2,4-Diamino-6-pyrimidinone;2,6-Diamino-3,4 -dihydropyrimidin-4-otu; 2,6-Diamino-4 (1H) -pyrimidinone; 2,6-Diamino-4 (3H) -pyrimidinone; 2,6-Diamino-4-hydroxypyrimidine; 2,6-Diamino-4 -pyrimidinol; 2,6-Diaminopyrimidin-4-otu;2,6-Diaminopyrimidine-4 (3H) -otu; 6-Aminoisocytosine; 6-Hydroxy-2,4-pyrimidinediamine; NSC 44914; NSC 680818; NSC9302;
Ngwongwo kemịkalụ nke 2,4-Diamino-6-hydroxypyrimidine
● Ọdịdị / Agba: ọcha siri ike
● Uzuoku Nrụgide:0.00232mmHg na 25°C
● Ebe Na-agbaze: 285-286 Celsius C (dec.) (ọkụ.)
● Ntụgharị uche: 1.7990 (atụmatụ)
● Ebe esi esi: 288.5 Celsius C na 760 mmHg
● PKA: 10.61± 0.50 (buru amụma)
● Ebe Flash: 128.3 Celsius C
PSA: 98.05000
● Njupụta: 1.84 g / cm3
● LogP: 0.50900
● Okpomọkụ nchekwa: Kpochapụ na +4°C
● Na-enwe mmetụta.: Ọ na-enwe mmetụta ọkụ
● Solubility.:DMSO (Obere), Methanol (Obere)
Ịdị ọcha/ịdị mma
99% * data sitere na ndị na-ebubata ngwaahịa
2,4-Diamino-6-hydroxypyrimidine *data sitere na ndị na-eweta reagent
Ozi nchekwa
● Foto:
Xi
● Koodu ihe egwu: Xi
● Okwu: 36/37/38
● Nkwupụta Nchekwa: 22-24 / 25-36-26
Bara uru
● Nkọwa: 2,4-Diamino-6-hydroxypyrimidine (DAHP) bụ onye na-ahọrọ, kpọmkwem ihe mgbochi nke GTP cyclohydrolase I, nkwụsị nke njedebe maka de novo pterin synthesis.Na mkpụrụ ndụ HUVEC, IC50 maka igbochi BH4 biosynthesis bụ ihe dịka 0.3 mM.Enwere ike iji DAHP gbochie mmepụta NO nke ọma n'ụdị cell dị iche iche.
● Na-eji: 2,4-Diamino-6-hydroxypyrimidine (DAHP) bụ onye na-ahọrọ, kpọmkwem ihe mgbochi nke GTP cyclohydrolase I, nkwụsị nke nkwụsị nke de novo pterin.Na mkpụrụ ndụ HUVEC, IC50 maka igbochi BH4 biosynthesis bụ ihe dịka 0.3 mM.Enwere ike iji DAHP gbochie mmepụta NO n'ụzọ dị irè n'ụdị cell dị iche iche. 2,4-Diamino-6-hydroxypyrimidine (cas # 56-06-4) bụ ngwakọta bara uru na njikọ organic.
2,4-Diamino-6-hydroxypyrimidine bụ ngwakọta kemịkalụ nwere usoro molekụla C4H6N4O.A na-ejikarị ya eme ihe dị ka etiti na njikọ nke ogige dị iche iche, gụnyere ọgwụ ndị na-emepụta ọgwụ na ihe na-esi ísì ụtọ. Ngwa ahụ nwere usoro mgbanaka pyrimidine nke nwere amino acid abụọ (NH2) na otu hydroxyl otu (OH) na-ejikọta na carbon carbon dị iche iche.Ihe owuwu a na-eme ka ọ bụrụ ngọngọ ụlọ dị iche iche maka njikọ nke ụmụ irighiri ihe dị mgbagwoju anya.2,4-Diamino-6-hydroxypyrimidine nwere ike nweta site na ụzọ dị iche iche nke sịntetik, gụnyere mmeghachi omume nke cyanamide na urea.Ọ nwere ọtụtụ ngwa na ụlọ ọrụ na-emepụta ọgwụ, karịsịa na njikọ nke ọgwụ anticancer na ọgwụ nje. N'ozuzu, 2,4-Diamino-6-hydroxypyrimidine bụ ihe dị mkpa nke na-achọta uru dị iche iche nke kemịkalụ na ngwa ọgwụ.
