Ngwaahịa
2,4-apughino-6-hydroxyyrimididine; Ọnọdụ Mba.: 56-06
Synnymts: 4 (1h) -pyrimidinone, 2,6-diamno- (8ci, 9ci); 2,4-omino-6-syroxyyrimirine; 2,4-syropyridididimin-6-1,6-raminone-4,6-diatyronone-4,6-syrino-4 (3h) -Priminone; 2,6-synonon-4-hydroxyyrimididine; 2,6-diamynol; 2,6-diamyrimididimididimine-4,6-aminopyysimine-4,6-hydroxymine; NSC 44914; NSC 680818; NSC9302;
Ihe akụrụngwa nke 2,4-synino-6-hydroxyyyyrimidine
● Njikọ / agba: White siri ike
● Nrụgide nke: 0.00232MHG na 25 Celsius C
● Point Point: 285-286 Celsius C (Dec.)
● rewansix: 1.7990 (atụmatụ)
● Esingtụ Isi: 288.5 Celsius C na 760 mmhg
PKA: 10.61 ± 0.50 (buru amụma)
Clash Point: 128.3 Celsius C
● ● 98.055
● Desensonity: 1.84 g / cm3
● Aggp: 0.50900
● Atchebe temp.:desiccate na + 4 Celsius C
● N'eche echiche.: Inwe mmetụta
● solubation.: tdMa (ntakịrị), methanol (ntakịrị)
Ozi Safety
● Tụọkwa (s):
Xi
Koodu obi ojoo: Xi
● Nkwupụta: 36/37/38
● Nkwupụta nchekwa: 22-24 / 25-36-26
Keibauru
Nkọwa: 2,4-omino-6-na-eme nhọrọ (Dahdyyyyrimididine (Dahp) bụ nhọrọ, onye akọwapụtara nke m, ọnụego na-amachi nzọụkwụ maka njikọta. Na sel Huvec, IC50 maka mgbochi nke BH4 biosynthesis bụ ihe dị ka 0.3 mm. Enwere ike iji Dahp mee ihe n'ụzọ dị iche iche enweghị mmepụta n'ọtụtụ ụdị sel.
● na-eji: 2,4-oadino-6-hydroxyyyrimididine (dahp) bụ nhọrọ, onye akọwapụtara GTPydydronase, m, ọnụego na-amachi usoro maka njikọta nke Novo Parten Partesis. Na sel Huvec, IC50 maka mgbochi nke BH4 biosynthesis bụ ihe dị ka 0.3 mm. Enwere ike iji Dahp na-egbochi ịrụpụta nke ọma n'ọtụtụ ụdị seno acylanan. ogige bara uru na njikọta Organic.
2,4-Ekwentị na 6-Hydroxyridimine bụ ọgwụ kemịkal nwere molecular C4H6N4O. A na-ejikarị ya dị ka nke etiti dị iche iche, gụnyere ọgwụ ọgwụ na dyness.The a na-enwe pydridine nwere otu ihe eji eme ihe (oh) jikọtara ọnụ carbon dị iche iche. Ihe owuwu a na - eme ka ọ bụrụ ihe mgbochi ụlọ dị iche iche maka njikọta molecules.2,4-syptino-6-na - enwe ike inweta site na usoro usoro ọmụmụ dị iche iche, gụnyere mmeghachi omume nke cyanamide na urea na urea. Ọ nwere ọtụtụ ngwa na ụlọ ọrụ ọgwụ, ọkachasị na nchịkọta ọgwụ ọgwụ na ọgwụ nje.
Nsị nke
2,4-Ekwentị na 6-Hydroxyridimine bụ ọgwụ kemịkal nwere molecular C4H6N4O. Ọ bụ ogige ihe ndị ọzọ nwere nke ezinụlọ pylimididic. A na-ejikọ usoro mgbanaka pyrimididine, otu amino (NH2) na ọnọdụ 2 na ọnọdụ anọ, yana otu hydroxy n'otu n'otu. Enwere ike igosipụta usoro kemịkalụ dịka: ammon | | H - C - C - N - C - C - NH2 | | Oh 2,4-omino-6-hydroxyridimine nwere ngwa dị iche iche na ụlọ ọrụ ọgwụ. Ọ bụ otu mgbọrọgwụ nke ọtụtụ ọgwụ, gụnyere ọgwụ mgbochi na ọgwụ ọgwụ ọgwụ. A na-ejikwa ya emepụta ọtụtụ analogs nucleotide nke eji na nyocha ọgwụ.
Na mgbakwunye na ngwa ọgwụ, a na-ejikwa akara ngosi 2,4-sydino-6-hydroxypyrimiridimitimidimidimidiridine ka ejikọrọ ya na agrochemicals. Ọ bụ ihe dị mkpa na njikọta ihe ọkụkụ na-eto eto na fungicides. Ọ dị ezigbo mkpa ịgbaso Protocol nchekwa mgbe ị na-eji 2,4-omino-6-sydypyyrimidipine. Ebe ọ bụ na ekewapụtara ya dị ka onye na-akpagbu kemịkalụ, ọ ga-eji ụdị ngwa nchekwa nke onwe ya mee ihe iji zere ịkpọtụrụ.
Na nchịkọta, 2,4-symino-6-hydroxyyrimididine bụ ihe organic compound nwere ngwa na ngwa na n'ọhịa ọgwụ na ubi ọrụ ugbo. Ihe owuwu kemịkalụ ya na-eme ka ọ baa uru dị ka etiti na usoro ọgwụ na ndị na-achị achị.
