Ngwaahịa
2,4-Diamino-6-hydroxypyrimidine
Njirimara Chemical Hydroxypyrimidine
| Ebe mgbaze | 285-286 Celsius C (dec.) (ọkụ) |
| Ebe esi nri | 234.22C (atụmatụ siri ike) |
| njupụta | 1.3659 (atụmatụ siri ike) |
| index refractive | 1.7990 (atụmatụ) |
| nchekwa okpomọkụ. | Debe n'ebe gbara ọchịchịrị, ikuku na-adịghị mma, okpomọkụ ụlọ |
| solubility | DMSO (obere), methanol (obere) |
| pka | 10.61± 0.50 (buru amụma) |
| ụdị | Ntụ ntụ kristal dị mma |
| agba | Ọcha ka ude |
| Mmetụta | Ìhè nwere mmetụta |
| Merck | 14,2981 |
| BRN | 125006 |
| InChiKey | SWELIMKTDYHAOY-UHFFFAOYSA-N |
| Ntuziaka dataBase CAS | 56-06-4(CAS DataBase ntụaka) |
| Ntuziaka Chemistry NIST | 4 (1H) -pyrimidinone, 2,6-diamino-(56-06-4) |
| Sistemụ ndekọ ihe EPA | 2,6-Diamino-4(1H) -pyrimidinone (56-06-4) |
Nkọwa ngwaahịa Hydroxypyrimidine
2,4-Diamino-6-hydroxypyrimidine bụ ngwakọta kemịkalụ nwere usoro molekụla C4H6N4O.Ọ bụ ngwakọta organic nke ezinụlọ pyrimidine.Ngwakọta ahụ nwere usoro mgbanaka pyrimidine, otu amino abụọ (NH2) jikọtara ya na ọnọdụ 2 na 4, na otu hydroxyl (OH) jikọtara ya na ọnọdụ 6.Enwere ike ịkọwa usoro kemịkalụ dị ka:Amonia ||H--C--C--C--N--C--C--NH2 ||oh 2,4-Diamino-6-hydroxypyrimidine nwere ngwa dị iche iche na ụlọ ọrụ ọgwụ.Ọ bụ etiti dị mkpa na njikọ nke ọtụtụ ọgwụ, gụnyere ọgwụ nje na antitumor.A na-ejikwa ya na-emepụta ọtụtụ nucleotide analogs eji na nyocha ọgwụ.
Na mgbakwunye na ngwa ọgwụ, a na-ejikwa 2,4-diamino-6-hydroxypyrimidine mee ihe dị ka ihe eji eme ihe na agrochemicals.Ọ bụ isi ihe dị mkpa na njikọ nke ndị na-ahụ maka uto osisi na fungicides.Ọ dị ezigbo mkpa ịgbaso ụkpụrụ nchekwa kwesịrị ekwesị mgbe ị na-eji 2,4-diamino-6-hydroxypyrimidine.Ebe ọ bụ na a na-ekewa ya dị ka ihe mgbakasị ahụ kemịkalụ, ekwesịrị iji nlezianya na-edozi ya ma na-eyi ihe nchebe zuru oke nke onwe iji zere kọntaktị kpọmkwem.
Na nchịkọta, 2,4-diamino-6-hydroxypyrimidine bụ ngwakọta organic nke nwere ngwa na mpaghara ọgwụ na ọrụ ugbo.Ọdịdị kemịkal ya na-eme ka ọ baa uru dị ka ihe etiti na njikọ nke ọgwụ na ndị na-ahụ maka uto osisi.
Ozi nchekwa
| Koodu egwu | Xi |
| Nkwupụta ihe egwu | 36/37/38 |
| Nkwupụta nchekwa | 22-24/25-36-26 |
| WGK Germany | 3 |
| Ihe edeturu egwu | Iwe iwe |
| TSCA | Ee |
| Koodu HS | 29335995 |
Ojiji Hydroxypyrimidine na Synthesis
| Nkọwa | 2,4-Diamino-6-hydroxypyrimidine (DAHP) bụ onye ahọpụtara, onye na-egbochi GTP cyclohydrolase I, nke na-ebelata ọnụego maka njikọ nke novo pterin.N'ime sel HUVEC, IC50maka mgbochi nke BH4biosynthesis bụ ihe dịka 0.3 mm.Enwere ike iji DAHP gbochie mmepụta NO nke ọma n'ụdị cell dị iche iche. |
| Njirimara kemịkalụ | Ọcha siri ike |
| Na-eji | 2,4-Diamino-6-hydroxypyrimidine (DAHP) bụ onye ahọpụtara, onye na-egbochi GTP cyclohydrolase I, nke na-ebelata ọnụego maka njikọ nke novo pterin.Na mkpụrụ ndụ HUVEC, IC50 maka igbochi BH4 biosynthesis bụ ihe dịka 0.3 mM.Enwere ike iji DAHP mee ihe n'ụzọ dị irè igbochi NO mmepụta n'ụdị cell dị iche iche.[Cayman Chemical] |
| Na-eji | Ọ na-eguzo na mmalite nke cascade nke enzyme-catalyzed nke na-amalite na carbohydrate carbon asaa a ma mechie na amino acid aromatic phenylalanine, tyrosine, na tryptophan. |
| Na-eji | 2,4-Diamino-6-hydroxypyrimidine (cas # 56-06-4) bụ ngwakọta bara uru na njikọ organic. |
| Ụzọ nke ịdị ọcha | Ọ recrystallis sitere na H2O.[Beilstein 25 III/IV 3642.] |
