L-Malic acid

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Aha ngwaahịa:L-Malic acid

Ụdị okwu:L-(-)-Malic acid, CP; Butanedioic acid, 2-hydroxy-, (2S)-;pinguosuan;Butanedioicacid,hydroxy-,(S)-;hydroxy-, (S)-Butanedioicacid;l-(ii) -malicacid;L-Gydroxybutanedioicacid;L-Mailcacid

CAS:97-67-6

MF:C4H6O5

MW:134.09

EINECS:202-601-5

Ụdị ngwaahịa:Mkpokọta osisi; Aliphatics; MalicAcidSeries; Carboxylic Acids (Chiral); Chiral chemicals; Chiral Reagents; Food & Feed ADDITIVES; Chiral Building Blocks; for Resolution of Bases; Optical Resolution; Synthetic Organic Chemistry; Ihe mgbakwunye nri na acidulant;Imidocyclic bc0001

Faịlụ Mol:97-67-6.mol

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Njirimara chemical nke Malic acid

Ebe mgbaze	101-103 Celsius C (ọkụ)
alfa	-2º (c=8.5, H2O)
Ebe esi nri	167.16°C (atụmatụ siri ike)
njupụta	1.60
uzuoku mgbali	0Pa na 25 ℃
index refractive	-6.5 Celsius (C=10, acetone)
FEMA	2655 \|L-MALIC Acid
Fp	220 Celsius C
nchekwa okpomọkụ.	Chekwaa n'okpuru +30 Celsius.
solubility	H₂O: 0.5 M na 20 Celsius C, doro anya, enweghị agba
ụdị	Ntụ ntụ
agba	Ọcha
Nnukwu ike ndọda	1.595 (20/4 ℃)
PH	2.2 (10g/l, H2O, 20℃)
pka	(1) 3.46, (2) 5.10 (na 25 ℃)
ngwa anya ọrụ	[α]20/D 30±2°, c = 5.5% na pyridine
Mmiri Solubility	soluble
Merck	14,5707
Nọmba JECFA	619
BRN	1723541
InChiKey	BJEPYKJPYRNKOW-REOHCLBHSA-N
LogP	-1.68
Ntuziaka dataBase CAS	97-67-6(CAS DataBase ntụaka)
Ntuziaka Chemistry NIST	Butanedioic acid, hydroxy-, (s)-(97-67-6)
Sistemụ ndekọ ihe EPA	Butanedioic acid, 2-hydroxy-, (2S)- (97-67-6)

Ozi nchekwa

Koodu egwu	Xi
Nkwupụta ihe egwu	36/37/38
Nkwupụta nchekwa	26-36-37/39
WGK Germany	3
RTECS	Ọnụ ego 7175000
TSCA	Ee
Koodu HS	29181980

Ojiji Malic acid na Synthesis

Nkọwa	L-Malic acid fọrọ nke nta ka ọ bụrụ isi (mgbe ụfọdụ ọ na-esighi ike, isi ísì) nwere tart, uto acidic.Ọ dịghị mkpa.Enwere ike ịkwadebe ya site na hydration nke maleic acid;site gbaa ụka si sugars.
Njirimara kemịkalụ	L-Malic acid fọrọ nke nta ka ọ bụrụ isi (mgbe ụfọdụ ọ na-esighi ike, na-esi ísì ụtọ).Ngwakọta a nwere tart, acidic, uto na-enweghị ntụpọ.
Njirimara kemịkalụ	ngwọta enweghị agba doro anya
Ihe omume	Na-eme na sap maple, apụl, egusi, pọọpọ, biya, mmanya vine, koko, sake, kiwi na mgbọrọgwụ chicory.
Na-eji	A na-eji L-Malic acid dị ka ihe mgbakwunye nri, Nhọrọ α-amino na-echebe reagent maka mmepụta amino acid.Synthon dị iche iche maka nkwadebe nke ogige chiral gụnyere κ-opioid agonists receptor agonists, 1α,25-dihydroxyvitamin D3 analogue, na phoslactomycin B.
Na-eji	Isomer na-emekarị bụ L-ụdị nke a chọtara na apụl na ọtụtụ mkpụrụ osisi na osisi ndị ọzọ.Nhọrọ α-amino na-echebe reagent maka ihe nrụpụta amino acid.Synthon dị iche iche maka nkwadebe nke ogige chiral gụnyere κ-opioid rece
Na-eji	Ọkara na njikọ kemịkalụ.Onye na-ahụ maka aghụghọ na nchekwa.Ihe na-atọ ụtọ, ihe na-eme ka ekpomeekpo na acidulant na nri.
Nkọwa	ChEBI: Ụdị ngwa anya na-arụ ọrụ nke malic acid nwere (S) nhazi.
Nkwadebe	Enwere ike ịkwadebe L-Malic acid site na hydration nke maleic acid;site gbaa ụka si sugar.
Nkọwa zuru oke	L-Malic acid bụ organic acid nke a na-ahụkarị na mmanya.Ọ na-arụ ọrụ dị mkpa na nkwụsi ike microbiological mmanya.
Omume biochem/physiol	L-Malic acid bụ akụkụ nke metabolism cellular.A na-amata ngwa ya na pharmaceutics.Ọ bara uru n'ịgwọ ọrịa ịba ọcha n'anya, dị irè megide hyper-ammonemia.A na-eji ya dị ka akụkụ nke ntinye amino acid.L-Malic acid na-ejekwa ozi dị ka nanomedicine n'ịgwọ ọrịa ụbụrụ ụbụrụ.A TCA (Krebs okirikiri) etiti na onye mmekọ na malic acid aspartate shuttle.
Ụzọ nke ịdị ọcha	Crystallize S-malic acid (icheku ọkụ) sitere na ethyl acetate / pet ether (b 55-56o), na-edebe okpomọkụ n'okpuru 65o.Ma ọ bụ igbari ya site refluxing na iri na ise akụkụ nke anhydrous diethyl ether, decant, itinye uche na otu ụzọ n'ụzọ atọ olu na crystallize ya na 0o, ugboro ugboro ka mgbe niile agbaze ebe.[Beilstein 3 IV 1123.]